NFL Week 6 odds, picks, how to watch: Expert predictions, survivor picks, best bets, teasers, and more

The 2022 NFL season is already more than 1 / 4 of the best way entire, however do not you dare avert your gaze, as a result of issues are simply beginning to get excellent. This weekend’s Week 6 slate is brim-full of highly spiced — and unpredictable — matchups, in all probability none more intriguing than the heavyweight conflict this is Bills as opposed to Chiefs.

As we do each week, we have now accrued the entire best alternatives and playing content material from and SportsLine and put them multi functional position, so you’ll be able to get alternatives towards the unfold from our CBS Sports mavens, in addition to further function content material for each and every sport, together with performs from height SportsLine mavens and the SportsLine Projection Model, best bets from our group of workers, survivor alternatives and more. 

All NFL odds by way of Caesars Sportsbook.

Which alternatives are you able to make with self belief in Week 6? And which Super Bowl contender is going down exhausting? Visit SportsLine, as its fantastic type simulates each NFL sport 10,000 occasions and is up nearly $7,000 for $100 avid gamers on top-rated NFL alternatives since its inception.

49ers at Falcons

Time: Sunday, 1 p.m. ET (Fox), flow on fuboTV (check out at no cost
Open: 49ers -6.5

Featured Game | Atlanta Falcons vs. San Francisco 49ers

“If we’re going to ding a franchise for a perceived bad roster, we need to give credit to a coaching staff for maxing out that roster. The Falcons have played five games and have been in five one-score games. Arthur Smith is doing a really good job with the current Falcons roster and deserves credit for navigating the Matt Ryan/Marcus Mariota swap. He had nothing to do with it and still has the offense giving people problems. If anyone gives these guys flak for using “smoke and mirrors,” quickly remind them that’s coaching. I’m going Niners here, but if the final injuries are bad for San Francisco I wouldn’t want to be on its side.”

That’s CBS Sports senior creator Will Brinson, cautiously backing the street favorites on this matchup of NFC squads. You can take a look at all of Brinson’s Week 6 predictions proper right here.

Patriots at Browns

Time: Sunday, 1 p.m. ET (CBS), flow on Paramount+ (click on right here)
Open: Browns -3.5

Featured Game | Cleveland Browns vs. New England Patriots

Bailey Zappe may be capturing the hearts of those in Foxborough, but it’s the defense that truly kept the Patriots afloat in Week 5 in their shutout win against the Lions. So far, New England’s defense has shown shutdown ability and ranks ninth in the NFL in DVOA. Not only do the Patriots have a high-level defense, but Bill Belichick is extremely familiar with Jacoby Brissett, whom he drafted back in 2016. … This will also be an opportunity for Rhamondre Stevenson to explode on the ground with Damien Harris sidelined. Cleveland’s run defense ranks 32nd in the NFL in DVOA.”

Tyler Sullivan, CBS Sports analyst and resident Patriots professional, is easily conscious that 61% of underdogs are protecting their video games, the best possible mark since 2004. So, he is in every single place New England as street ‘canine towards Cleveland. Check out all of his Week 6 projections proper right here.

Jets at Packers

Time: Sunday, 1 p.m. ET (Fox), flow on fuboTV (check out at no cost
Open: Packers -9.5

Featured Game | Green Bay Packers vs. New York Jets

Aaron Rodgers enters this one moderately banged up, however the Packers are out for redemption after falling to the Giants in London per week in the past. Are they up for the problem? SportsLine’s Projection Model, which simulates each NFL sport and has overwhelmed more than 94% of CBS Sports Football Pick’em avid gamers 4 occasions over the last six years, indisputably thinks so. We can let you know that the type has Green Bay protecting a 7.5-point unfold towards the Jets in nearly 60% of simulations, making the Packers one among its more potent backs of Week 6. Check out more from SportsLine in this matchup, and different type bets, proper right here.

Jaguars at Colts

Time: Sunday, 1 p.m. ET (CBS), flow on Paramount+ (click on right here)  
Open: Colts -2.5

Featured Game | Indianapolis Colts vs. Jacksonville Jaguars

(*6*) That’s Tyler Sullivan, backing Jacksonville at the “Pick Six NFL Podcast,” the place John Breech and Will Brinson had been similarly as bullish at the underdogs: “The past 15 times they’ve met,” Breech famous, “Jacksonville is 13-1-1 against the spread.” Brinson additionally famous that he’d be prepared to wager the Under, taking into account the unsightly nature of those two offenses.

Brinson and the fellows additionally ruin down each different Week 6 sport at the “Pick Six NFL Podcast.” Listen and subscribe right here.

Vikings at Dolphins

Time: Sunday, 1 p.m. ET (Fox), flow on fuboTV (check out at no cost
Open: PK

Featured Game | Miami Dolphins vs. Minnesota Vikings

Just in case it is Skylar Thompson at quarterback for the Dolphins: “There have been five starts since 2000 by rookie QBs drafted in the seventh round. They are 0-5 straight up and 0-5 against the spread. … (Meanwhile), I’m not sure the Vikings are Super Bowl contenders, but I love Justin Jefferson and Dalvin Cook. Jefferson leads all receivers with 547 yards and is coming off of a 154-yard performance, and then this weekend is very special for Cook. The Vikings star running back grew up in Miami and is going to have “numerous supporters” at this matchup, consistent with He stated this weekend is ‘what I dreamed about,’ so be expecting a large sport from him. I really like getting this quantity at 3 issues.”

CBS Sports NFL analyst Jordan Dajani is obviously within the inexperienced together with his straight-up alternatives this yr, and he is purchasing the Vikings as giant winners even at the street. Check out all of Dajani’s Week 6 alternatives proper right here.

Bengals at Saints

Time: Sunday, 1 p.m. ET (CBS), flow on Paramount+ (click on right here)
Open: Bengals -1

Featured Game | New Orleans Saints vs. Cincinnati Bengals

“The Bengals have lost three tough games in the final seconds and are playing a second straight road game after losing to the Ravens. The Saints won last week behind Taysom Hill, but can they count on that every week? The Saints defense has been a big disappointment, so Joe Burrow will return to Louisiana and get a victory because of it.”

That’s CBS Sports senior columnist Pete Prisco, who thinks the Bengals deserve to be giant favorites at the street, even after their unsightly loss to Baltimore ultimate Sunday night time. You can take a look at alternatives for each unmarried Week 6 sport from Prisco, who went 9-1 on his height prop bets per week in the past, proper right here at CBS Sports.

Ravens at Giants

Time: Sunday, 1 p.m. ET (CBS), flow on Paramount+ (click on right here)
Open: Ravens -5.5

Featured Game | New York Giants vs. Baltimore Ravens

The SportsLine Projection Model, which simulates each NFL sport 10,000 occasions, enters Week 6 of the 2022 NFL season on a 146-106 run on top-rated NFL alternatives relationship again to the 2017 season, returning over $7,000 for $100 avid gamers since its inception. This week, the type has recognized a staff on this matchup between the Ravens and Giants as a an important piece of a five-team parlay that might lead to a 25-1 payout. Check out the overall parlay projection proper right here at SportsLine.

Buccaneers at Steelers

Time: Sunday, 1 p.m. ET (CBS), flow on Paramount+ (click on right here)
Open: Buccaneers -6.5

Featured Game | Pittsburgh Steelers vs. Tampa Bay Buccaneers

Tom Brady and the Buccaneers have not been best right through their 3-2 get started, however few groups were much less aggressive than Mike Tomlin’s Steelers, who at the moment are on their 2nd QB post-Ben Roethlisberger and were given torched through the Bills in Week 5. Pittsburgh may get pleasure from returning house, however Matt Canada’s offense does not seem to have the revel in nor the cohesiveness to fit Brady and Co., who’re getting primary contributions from Leonard Fournette within the passing sport. It’s no wonder, then, that SportsLine professional R.J. White, who is long past 32-19-3 on NFL alternatives via Week 5, likes Tampa Bay as one among his teaser alternatives for this weekend’s motion.

R.J. has more on why the Bucs are value backing, plus a couple of different particular teaser alternatives for Week 6, over at SportsLine, which you’ll be able to take a look at proper right here.

Panthers at Rams 

Time: Sunday, 4:05 p.m. ET (Fox), flow on fuboTV (check out at no cost)  
Open: Rams -9.5

Featured Game | Los Angeles Rams vs. Carolina Panthers

“Carolina pulled the plug on the Matt Rhule era, firing the head coach after just two and a half seasons. Despite the coaching turnover (defensive coordinator Phil Snow and assistant special teams coach Ed Foley were also fired), this could be a nice rebound spot for the Panthers. In these situations, teams do get a little boost the following game and Carolina now faces a Rams team that has struggled mightily to begin the season. Offensively, L.A.’s 4.8 yards-per-play average is tied for the lowest in the NFL and they are pressuring the QB on just 24% of plays, which ranks 31st in the NFL. … This is a good spot to take the points.”

CBS Sports’ Tyler Sullivan is selecting the Rams to win however the Panthers to quilt on this doubtlessly unsightly slugfest between two determined groups. Catch more of Sully’s research, and predictions for each different Week 6 sport, proper right here.

Cardinals at Seahawks

Time: Sunday, 4:05 p.m. ET (Fox), flow on fuboTV (check out at no cost
Open: Cardinals -2.5

Featured Game | Seattle Seahawks vs. Arizona Cardinals

Geno Smith is, statistically, probably the most environment friendly QBs within the NFL at this time. Kyler Murray, regardless of all his skill, is maximum surely now not. And but the Cardinals are liked at the street on this divisional matchup. Don’t purchase it, says SportsLine professional R.J. White, who is tabbed Seattle as one among his SuperContest alternatives for Week 6. R.J. is aware of his stuff — he is 329-250-21 all-time in SuperContest predictions, and as soon as for tied for seventeenth out of just about 2,800 contestants within the Westgate Las Vegas pageant — so you have got quite a few reason why to believe him leaning the Seahawks’ method.

R.J. has more on Seattle, plus 4 different SuperContest alternatives for Week 6, at SportsLine proper right here.

Bills at Chiefs

Time: Sunday, 4:25 p.m. ET (CBS), flow on Paramount+ (click on right here)
Open: PK

Featured Game | Kansas City Chiefs vs. Buffalo Bills

“I can’t say this for sure, but I feel like the Bills’ entire offseason plan revolved around one thing: Adding players who could help them beat the Chiefs. Their biggest signing was Von Miller, who was brought in for this exact type of game. He’s someone who should be able to get some pressure on Patrick Mahomes, which is something the Bills didn’t do a good job of in January. To me, this feels like a revenge game. … All the Bills have been thinking about all offseason is 13 seconds. They were 13 seconds away from an AFC title game appearance, they were 13 seconds away from finally beating Patrick Mahomes in the playoffs and now, I’m 13 seconds away from making my prediction for the game. The Bills are an unstoppable freight train right now.”

CBS Sports NFL analyst John Breech is aware of Mahomes almost definitely merits more credit score, being a house underdog in one of these giant spot, however he is in every single place Buffalo on this rematch of ultimate yr’s Divisional Round shootout. Check out all of his Week 6 alternatives right here

Cowboys at Eagles

Time: Sunday, 8:20 p.m. ET (NBC), flow on fuboTV (check out at no cost
Open: Eagles -5.5

Featured Game | Philadelphia Eagles vs. Dallas Cowboys

NFL professional Emory Hunt Jr., founding father of Football Gameplan and former Louisiana-Lafayette working again, is aware of precisely how to learn the Eagles, who input “Sunday Night Football” taking a look to keep unbeaten. He’s 36-21-1 in his ultimate 58 alternatives involving Philly, returning $1,271 to bettors. He is aware of the Birds have probably the most balanced offenses within the sport, however he is additionally now not shortchanging the Dallas protection on this one. We can let you know Hunt is leaning Over for this prime-time NFC East brawl, however he is were given a complete forecast for the matchup, together with an unique ATS projection, proper right here at SportsLine.

Broncos at Chargers

Time: Monday, 8:15 p.m. ET (ESPN), flow on fuboTV (check out at no cost
Open: Chargers -4

Featured Game | Los Angeles Chargers vs. Denver Broncos

It’s exhausting to know precisely what to make of the Chargers at any given time. Justin Herbert and Austin Ekeler are consistent manufacturers, however Brandon Staley’s decision-making, regardless of how analytically sound, has left quite a few enthusiasts scratching their heads right through a 3-2 get started. One man who does have a cast care for on Los Angeles: SportsLine professional R.J. White, who’s 17-6-1 in his ultimate 24 ATS alternatives that includes the Chargers. The No. 1 ATS NFL professional on alternatives from 2017-2021, when he returned over $2,500 to $100 avid gamers, he is were given a complete breakdown of Monday night time’s matchup with Russell Wilson and the Broncos over at SportsLine. Check out his Over/Under name, plus an in depth ATS select you can wanna lock in, proper right here.

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